“I kind of liked being the wicked bitch…”
Her first scene playing Addison in the Season 1 finale changed her life forever:
"That entrance [at the end of Season 1] that changed my life. I got more calls and attention from that 60-second scene than anything in my career before. Isn’t that funny? Shonda [Rhimes] is a genius."
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And she fully embraced playing the "wicked bitch":
"Everyone hated me, but at that time there was no Twitter. There were chat rooms, but I never really went on them. I kind of liked being the Wicked Witch from the east. Or the wicked bitch. Shonda’s really gifted at flipping every character that’s seemingly awful. It’s a great lesson in how to have compassion for people that you initially hate."
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She (along with the rest of America) was shocked when the show killed off her on-screen ex-husband Derek "McDreamy" Shepherd:
"I was surprised when they killed off Patrick [Dempsey]. It had been so long and I was like, 'Oh, really?' And I tuned into that episode. It was like, 'Oh, I guess I should watch this.'"